Product ID:TECHNE SCAN MDP TECHNETIUM TC99M MEDRONATE
MSDS Date:01/01/1992
FSC:6505
NIIN:00N030330
MSDS Number: BNNTM

MALLINCKRODT MEDICAL INC

2703 WAGNER PLACE
MARYLAND HEIGHTS, MO 63043
US

Emergency Phone: 314-344-3800

Info Phone: 314-344-3800

Cage: FO650

MALLINCKRODT MEDICAL INC

MARYLAND HEIGHTS, MO 63043-3421 US

Telephone: 314-770-7800/314-895-2000

Cage: FO650

(ORAL,RAT)700

CAS: 7772-99-8

RTECS: XP8700000

Fraction By Weight: 9.1%

OSHA PEL 2 MG/M3 (SN)

ACGIH TLV: 2 MG/M3 (SN)

MEDRONIC ACID

CAS: 1984-15-2

Fraction By Weight: 90.9%

LD50 LC50 Mixture:SEE INGREDIENT 1
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:HAZ INGRED FOUND IN TECHNESCAN MDP ARE
SKIN AND EYE IRRITANTS, BUT DUE TO SMALL QTY PRESENT IN EACH
CONTAINER, NO ADVERSE HEALTH EFFECTS ARE EXPECTED TO OCCUR FROM
EXPOS. INHAL/INGEST/SKIN/ EYE: NOT E XPECTED TO BE HLTH HAZ.
CHRONIC: NOT EXPECTED TO BE CHRONIC HEALTH HAZARD. ALTHOUGH THIS
KIT ITSELF (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLT HAZ: DOES NOT REQUIRE A WARNING, WHEN THE
KIT IS RECONSTITUED WITH TECHNETIUM-99M, THE MATERIAL BECOME
RADIOACTIVE. RADIOACTIVE MATERIALS ARE SUBSTANCES KNOWN TO THE
STATE OF CALIFORNIA TO CAUSE R EPRODUCTIVE TOXICITY.
Medical Cond Aggravated by Exposure:NO INFORMATION FOUND.

First Aid:INHAL: REMOVE TO FRESH AIR. SUPPORT BRTHG. (GIVE O2/ARTF
RESP) . INGEST: CALL MD IMMED . SKIN: WASH EXPOSED AREA WITH SOAP
AND WATER. GET MED ADVICE IF IRRITATION DEVELOPS. EYE: WASH THORO
UGHLY WITH RUNNING WATER FOR AT LEAST 15 MIN. GET MED ADVICE IF
IRRITATION DEVELOPS.

Extinguishing Media:USE ANY MEANS SUITABLE FOR EXTINGUISHING
SURROUNDING FIRE.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA AND FULL
PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:NOT CONSIDERED TO BE A FIRE/EXPLOSION.

Spill Release Procedures:COLLECT NON-RADIOACTIVE SPILLS & DISPOSE OF
MATL AS NON-HAZ WASTE. FOR TECHNESCAN MDP RECONSTITUTED W/SODIUM
PERTECHNETATE TC99M: IF ANY LOSS/REL OF RADIOACTIVE CONTENTS
OCCURS, NOTIFY YOUR SFTY DEPT & MALLINCKRODT @ (314)344-3800. ALL
(SUPP DATA)
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:DRUG SHOULD BE STORED @ 2C-8C, BOTH
PRIOR TO & FOLLOWING RECONSTITUTION W/SODIUM PERTECHNETATE TC-99M &
DISCARDED AFTER 6HRS FROM TIME OF PREPARATION.
Other Precautions:AFTER RECONSTITUTION, HNDLG TIME SHOULD BE KEPT TO A
MINIMUM, & APPROP SHIELDING SHOULD BE USED. HNDLG DEVICES SUCH AS
SYRINGE & TONGS SHOULD BE USED. STOR & DISP OF PROD SHOULD BE
CONTROLLED IN A MAN NER THAT IS IN COMPLIANCE (SUPP DATA)

Respiratory Protection:NOT EXPECTED TO REQUIRE PERSONAL RESPIRATOR
USUAGE. USE NIOSH/MSHA APPROVED RESPIRATOR APPROPRIATE FOR EXPOSURE
OF CONCERN .
Ventilation:NOT EXPECTED TO REQUIRE ANY SPECIAL VENTILATION.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:CLEAN BODY-COVERING CLOTHING.
Work Hygienic Practices:AS PART OF GOOD LAB & PERSONAL HYGIENE & SFTY
EXPOS TO THE CHEM SUBSTANCE & ENSURE PROMPT REMOVAL FROM
SKIN/EYES/CLTHG.
Supplemental Safety and Health
SPILL PROC: CLEANUP OPERATIONS SHOULD BE PERFORMED ACCD TO STD
OPERATING PROC ESTABLISHED FOR YOUR FACILITY. OTHER PREC: WITH
APPROPRIATE REGULATIONS OF THE GOVERNMENT AGENCY AUTHORIZED TO
LICENSE THE USE OF THIS RADIONUCLIDE.

HCC:N1
Boiling Pt:B.P. Text:212F,100C
Melt/Freeze Pt:M.P/F.P Text:32.0F,0.0C
Solubility in Water:SOLUBLE
Appearance and Odor:SM, DRY, WHITE CRYSTALS CLINGING TO INSIDE OF 10 ML
GLASS VIALS, ODORLESS

Stability Indicator/Materials to Avoid:YES
NO INFORMATION FOUND.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:WHEN HEATED TO DECOMPOSITION,
SUBSTANCE MAY EMIT OXIDES OF CARBON AND CORROSIVE FUMES OF
HYDROCHLORIC ACID.

Waste Disposal Methods:RADIOACTIVE WASTE SHOULD BE DISPOSED OF
ACCORDING TO SOPS ESTABLISHED BY YOUR RADIATION SAFETY OFFICER.
ENSURE COMPLIANCE WITH LOCAL, STATE AND FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.